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Article
April 8, 1893

TRICHLORACETIC ACID; AS A TEST FOR ALBUMIN; AS A CAUSTIC; AND AS AN ASTRINGENT.

JAMA. 1893;XX(14):383. doi:10.1001/jama.1893.02420410007001e

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Abstract

As bed-side tests for albumin in the urine, the test-papers put on the market by manufacturing pharmaceutists leave little to be desired, as to convenience. But for office use, the most convenient reagent we have used for the quick, certain and ready test for albumin in the urine, is trichloracetic acid.

Place two to four drachms of suspected urine—filtered, if necessary—in a small graduate glass, drop into the urine one or two small crystals of the acid, gently stir the urine with a small glass rod, aluminum probe or clean splinter of wood; and if albumin be present in appreciable proportion, it will quickly settle at the bottom of the glass, as a white flocculent deposit.

The proportion of albumin can thus be quickly estimated, per volume, by reading the graduate marks, sufficiently accurate for ordinary purposes, consuming only a very few minutes, little trouble or expense, or skill.

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