"The disease known as epilepsy is probably the most disheartening condition as to treatment that the physician has to deal with, since it often resists the influences of all standard remedies, and drives the practitioner from drug to drug in the hope of finding one which will be at least alleviating in its effects."—(Hare, "Practical Therapeutics," p. 496.)
Soon after beginning service in the Northern Indiana Hospital for Insane, in the summer of 1894, I began to make a careful, systematic study of the male epileptics with a view of ameliorating their condition as much as possible. Among the 300 males in the hospital there are always present from 30 to 35 epileptics, changes being comparatively few. All are well marked cases and exhibiting every grade of mental decay. Simple cases with few convulsions and without decided mental change are not admitted to the hospital.
Syphilitic, toxic and apoplectic convulsion
HESSLER R. EPILEPSY AND ERYSIPELAS. JAMA. 1898;XXX(20):1157–1159. doi:10.1001/jama.1898.72440720021001f
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