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March 30, 1900


JAMA. 1900;XXXVI(13):897. doi:10.1001/jama.1900.02470130045010

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The usual symptoms of thyroidism, emaciation, weakness, shortness of breath, nervousness, etc., are well known, but there are others occasionally observed that are less generally appreciated. If we are to regard exophthalmic goiter as the result of hyperthyroidization, we can see possibilities in the way of unpleasant symptoms that have not all been actually observed from the therapeutic use of the extract. However that may be, it is probable that observations on the increasing therapeutic use of the drug will from time to time bring out many important additions to our knowledge of its effects. One such has been editorially noticed in the Medical Press and Circular for March 6. The reference to the record is not given, but it states that Dr. Coppez, of Brussels, reports the cases of five patients, four of them women, in whom prolonged thyroid treatment for obesity produced well-marked optic neuritis, occurring several months

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