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Article
June 1, 1901

THE VERMIFORM APPENDIX THE CONSERVATORY FOR THE COLON BACILLUS.

JAMA. 1901;XXXVI(22):1565. doi:10.1001/jama.1901.02470220039009
Abstract

From experiments upon animals Kohlbrugge1 has learned that when the stomach is empty it may be quite sterile, whereas during digestion it is possible to cultivate numberless bacteria from the ingesta. The small intestine when empty is also sterile; wherever the ingesta occur there bacteria are also found. This periodical cleansing of the small intestine he designates as autosterilization. He never found the cecum or colon sterile, the bacterium coli commune being the predominating variety and especially numerous in the cecum. The cecum is therefore the breeding place of the colon bacilli, which are peculiar to the individual and persist from the earliest extra-uterine period till some time after death. The cecum is the brood-oven of the body and here develop the bacteria, which are our constant messmates. That these bacteria may be of some physiologic importance is not unreasonable. The vermiform appendix, not subjected to the peristalsis which

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