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Cases of this interesting form of echinococcus disease occasionally occur in the United States, especially in immigrants from Southern Germany and certain parts of Austria, Switzerland, and Russia, where the disease is not so very infrequent. Recently, Melnikow-Raswedenkow published an extensive monograph based on the study of the parasitology, general pathology, and pathologic anatomy of about one hundred cases from various museums and laboratories of Europe. In Russia the disease is more frequent than commonly thought, and it appears to be of rather wide distribution. Among some of the principal results obtained by Melnikow-Raswedenkow may be mentioned that the disease may be primary not only in the liver, but also in other organs such as the brain, the spleen and the adrenals. The peculiar changes produced in the tissues depend on the growth of the parasite itself, rather than on the nature of the reactions of the cells, so that
ECHINOCOCCUS ALVEOLARIS SIVE MULTILOCULARIS. JAMA. 1901;XXXVI(25):1788. doi:10.1001/jama.1901.02470250042009
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