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Article
August 3, 1901

RETENTION OF DIPHTHERIA BACILLI IN THE VENTRICLES OF THE LARYNX.

JAMA. 1901;XXXVII(5):333. doi:10.1001/jama.1901.02470310039008
Abstract

It has now been firmly established, and it is generally recognized, that diphtheria bacilli may be present in the throat in the absence of symptoms of diphtheria, lodgment, but not infection, taking place; and also that the bacilli may be found in the throat long after recovery from the disease has occurred. A further possible site and source of infection that is likely to escape detection, unless specifically looked for, is pointed out by Dr. W. J. Horne,1 namely, the ventricles of the larynx. This observer relates the case of a child, nine months old, who presented symptoms of laryngeal obstruction requiring tracheotomy, but no positive evidence of dipththeria, as an instance of which it was nevertheless regarded. Treatment with antitoxin was instituted, but death ensued. On postmortem examination, the pharynx and the larynx were found free from membrane, and cultures from these parts failed to disclose the presence

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