It seems not impossible that the presence of oxalic acid in the body in undue amounts may be attended with a more or less well-defined group of manifestations, but the subject is one that is surrounded with a good deal of uncertainty. As the result of an experimental and clinical investigation undertaken a few years ago, Dr. Helen Baldwin1 arrived at the opinion that as varying amounts of calcium oxalate may be held in solution in the urine, conclusions based upon the presence or number of calcium-oxalate crystals found therein are of no real value as an indication of the quantity of oxalic acid present. Unless the utmost care is exercised, the results obtained by quantitative estimations of oxalic acid are subject to large percentages of error. An ordinary mixed diet regularly contains traces of oxalic acid or its salts. A portion of the oxalic acid ingested with the
CONCERNING THE PRESENCE OF OXALIC ACID IN THE ORGANISM. JAMA. 1901;XXXVII(7):452–453. doi:10.1001/jama.1901.02470330034003
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