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Article
August 24, 1901

BALANTIDIUM COLI THE CAUSE OF CHRONIC DIARRHEA.

JAMA. 1901;XXXVII(8):518. doi:10.1001/jama.1901.02470340036005
Abstract

Solowjew1 describes a carefully studied instance of chronic diarrhea in a man of 54, in whose fecal discharges were found numerous balantidia coli. Enemas of tannin and the internal administration of tannoform had no effect. The diarrhea continued with living parasites in the discharges, and death resulted. At the postmortem nothing remarkable was found in any other organ except the large intestine, which was the seat of large ulcerations throughout. The ulcers were rounded or oval as well as irregular, up to 1 cm. and more in diameter, their long diameter running transversely, the margins usually more or less thickened and nodular. The nodules were somewhat reddish and yielded on incision a juice which contained balantidia filled with red corpuscles. The floor of the ulcers often reached to the muscular coat and in some of the larger to the serous. Between the ulcers the mucous membrane was reddened and

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