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August 31, 1901


JAMA. 1901;XXXVII(9):583-584. doi:10.1001/jama.1901.02470350039007

Recent investigations with the aid of modern methods have shown conclusively that the gonococcus may invade the general circulation and cause an acute endocarditis, which usually assumes a malignant, destructive character. This demonstration, among many others one might cite, is an excellent illustration of the advantages that result from efforts to determine the exact nature of inflammatory and infectious processes by placing the diagnosis upon an etiologic basis. Our respect for the gonococcus and for vulgar gonorrhea has increased greatly since the pathogenic possibilities of micrococcus gonorrheæ have been shown to equal those of the most virulent of microbes. Recently, Prochaska has described additional cases of general gonococcal infection from Professor Eichhorst's clinic in Zurich.2 In one case gonococci were demonstrated by microscopic and cultural methods in the endocardial vegetations of a young man in whom polyarthritis and acute aortic endocarditis developed soon after onset of an ordinary gonorrhea.