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July 9, 1898


JAMA. 1898;XXXI(2):76-78. doi:10.1001/jama.1898.02450020032008

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In a disease so prevalent and wide-spread as typhoid, necessarily lesions of any and all systems occur, some of which may be regarded as accidental and casual, while others from the comparative frequency with which they exist must be looked upon as in the nature of complications. Indeed, a third class may be added, that of intercurrent affections, those diseases which might with great probability never have occurred had not the resisting power of the economy become so impaired by the ravages of the disease that ready entrance is allowed to the specific organisms of other affections, which in a healthy state of the body could not have obtained a foothold. Of these germs streptococci, staphylococci and pneumococci, play a leading part; they also contribute largely to what might be called the complications proper, while late reports show that the typhoid bacillus itself is amply able to produce some of

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