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This monograph opens up with a brief description of the development of the uterus and its anatomic relations. Uterine myomata are then considered in an exhaustive manner. The histology of the uterus in relation to its neoplastic pathogeny, the influence of aberrant elements, "rests," developmental irregularities, gross malformations, and the microbic theory are all considered under the etiology of these new growths. The author thinks that suppressed maternity and sterility "are among the most important factors in the genesis of these tumors."
Is it not more probable that the diminished fertility of these patients is due rather to the pathologic state of the uterus superinduced by the presence of the new growths? Nor does his point find support when he attempts to show the hereditary nature of these growths, for he states "myomatous patients come of large families, for those in my list averaged 8.1 members each." Concerning the etiology
Uterine Tumors: Their Pathology and Treatment. JAMA. 1901;XXXVII(9):593. doi:10.1001/jama.1901.02470350049023
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