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October 26, 1901


JAMA. 1901;XXXVII(17):1119-1120. doi:10.1001/jama.1901.02470430043004

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Some new light has been thrown upon the manner in which the heart hypertrophies, and upon the causes that lead to cardiac hypertrophy both under physiological and pathological conditions, by the important work of Carl Hirsch.1 Hirsch approached the problem in a somewhat different manner than previous observers; he employed more exact methods of study in that he separated the walls of the four cavities and considered each as an entity. This permitted the consideration of the relation of the mass of each cavity to that of the entire heart and of the general musculature of the body in health as well as in various diseases. It appears that the mass of the heart muscle is an expression solely of the work it accomplishes and that in sound individuals there is an intimate and direct relationship between the activity of the heart and the activity of the general

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