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The fact that I was able to find fat necrosis in three cases, and to learn of a fourth case in the course of two weeks, all of such cases either coming to autopsy or observed during surgical procedure, would indicate the probability that fat necrosis is not infrequently associated with gallstones, and that there is a necessity for more effort to differentiate gallstones with necrosis from gallstones without it.
So far as our information at the present time would indicate, the only immediate value of such a differentiation would be in the line of prognosis. It is reasonable to conclude that more accurate and extensive observation would eventually lead to betterment of treatment, either in the matter of improved surgical technique, new surgical procedure or improved treatment along medicinal lines.
Many authors have written of gallstones as prominent etiologic factors in fat necrosis, and in lesser measure in pancreatic
EVANS WA. A REPORT OF FOUR CASES OF FAT NECROSIS IN CONNECTION WITH GALLSTONES. JAMA. 1901;XXXVII(18):1176–1180. doi:10.1001/jama.1901.62470440026001g
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