It seems a not unreasonable assumption that the self-limited infectious diseases should be amenable to successful treatment with the antitoxic products of their causative factors. This has been demonstrated on a large scale in the instance of diphtheria, less extensively in that of tetanus and plague, and doubtfully in that of streptococcus infection, pneumonia, typhoid fever and dysentery. Erysipelas is dependent upon a streptococcus, which it is thought is identical with or closely related to the streptococcus pyogenes. Any immunity conferred by an attack of this disease must be brief, as the attack appears to predispose to rather than confer protection against subsequent attacks. It is true that some French observers have reported favorable results in the treatment of erysipelas with antistreptococcic serum, but this experience has not been universal.
Believing that the antitoxins of erysipelas are retained for but a short time in the bodies of those suffering from
THE TREATMENT OF ERYSIPELAS WITH THE SERUM OF ERYSIPELATOUS PATIENTS. JAMA. 1901;XXXVII(18):1185–1186. doi:10.1001/jama.1901.02470440035005
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