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November 2, 1901


JAMA. 1901;XXXVII(18):1187. doi:10.1001/jama.1901.02470440037009

The appearance in this issue—pages 1176 and 1180— of two articles on fat necrosis in its relation to gallstones may serve to attract attention to the close associationship between cholelithiasis and inflammatory diseases of the pancreas in the course of which more or less disseminated fat necrosis may arise. The addition to the classical picture of biliary colic of certain peculiar fea tures to which attention is directed by Dr. Beck and by Dr. Evans is certainly a point sure to interest the clinician and to stimulate him to closer study of diseases involving the region of the duodenal end of the pancreas. The intense abdominal pain and the cyanosis, especially of the abdominal walls, which Halsted found among the most striking clinical features in the now classical case, in which acute hemorrhagic pancreatitis and fat necrosis was shown by Opie to be associated with the impaction of a biliary