Looking backward over the history of the treatment of the diseases of the urethra, if one is impressed with the slight amount of real progress that has been made, there is less cause for surprise if the fact is taken into consideration that our knowledge of the nature itself of these diseases, certainly until the last fifteen years, has been very slight. Known in ancient days to be an entity by itself, urethritis came to be considered as another manifestation of syphilis from early in the sixteenth until the middle of the last century. Neisser's discovery of the gonococcus in 1879, and particularly the discoveries of Pasteur. Metchnikoff and others as to the nature of infecting diseases and the way the body reacts against them, have acted as guideposts, showing the way towards their proper treatment, although the information from this source as regards their treatment through a misrepresentation of
GREENE RH. FALLACIES IN THE TREATMENT OF URETHRAL DISEASES.. JAMA. 1901;XXXVII(19):1223–1227. doi:10.1001/jama.1901.62470450003001a
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