In no disease which the general practitioner has to treat is an accurate and prompt diagnosis of more importance than it is in diphtheria. It is practically undisputed that a true diphtheritic exudate is caused by the Klebs-Löffler bacillus. It is a fact now established and generally accepted that many of the diseases which have as a sign a membranous exudation in the throat are not diphtheria. It is also established that a true diphtheritic exudation may exist in other portions of the body than the throat, and it is well known that true diphtheria bacilli may exist in a throat free from any exudate, and in a person entirely free from clinical signs of any disease. Another important fact, long ago pointed out by Jacobi and other observers, is that true diphtheria, capable of transmitting the disease, frequently passes under the form and guise of some benign throat affection,
FUSSELL MH. THE VALUE OF THROAT CULTURES IN DIPHTHERIA. JAMA. 1901;XXXVII(20):1287–1289. doi:10.1001/jama.1901.62470460001001
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