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November 30, 1901

Cause of Asthma.

JAMA. 1901;XXXVII(22):1476. doi:10.1001/jama.1901.02470480046016

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Depew, N. Y., Nov. 18, 1901.

To the Editor:  —In your report of the meeting of the New York State Medical Association last month, you stated that my "idea is that asthma arises from an inability of the blood to carry the requisite quantity of oxygen," whereas I claimed that this abnormality of the blood causes but one variety of asthma, the asthmatic anematosis. The dyspnea in the other varieties of asthma, i. e., the asthmatic lymphocytosis and the asthmatic toxic leucocytosis, is due largely to a tubular obstruction from the disintegration of an unstable blood, which in the lymphocytic variety fills the air tubes with lymph and mucus; that together with the collateral engorgement of the lymph capillaries nearly closes the lumen of the air tube, while in the toxic leucocytic variety the glands in the larynx and air-tubes are enlarged, producing the wheeze and dyspnea.Yours respectfully,

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