The comparative infrequency of lesions of the cornea as manifestations or results of acquired syphilis, and the opinion of many ophthalmologists, among others Mooren, Panas and Perrin (according to Denarié) that corneal lesions are not caused by acquired syphilis, have prompted me to present this subject for the consideration of the Section on Ophthalmology, and to report some cases that have come under my own observation in which the relation of cause and effect seems to be clear.
The relation of inherited syphilis to interstitial keratitis seems to be well established, and the etiology of the disease can usually be fairly demonstrated in a large majority of the cases. But in a considerable number of cases of deep-seated inflammation of the cornea which simulate in many respects the interstitial keratitis of inherited syphilis, no confirmatory evidence of such taint can be shown; and it is in such cases that careful
WILDER WH. CORNEAL LESIONS IN ACQUIRED SYPHILIS. JAMA. 1901;XXXVII(25):1669–1671. doi:10.1001/jama.1901.62470510025001g
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