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First having my attention called to the efficacy of specific treatment in a case of albuminuria, in which I gave the mixed treatment of potassium iodid ard mercury bichlorid for specific trouble, I was greatly surprised to see the albumin disappear, instead of its being increased by the supposed irritant properties of the iodid (as I had been taught it was "hard" on the kidneys), and was led to make a series of experiments in an effort to discover the modus operandi of this mixture, and whether it was the iodid or the mercury that produced the result, also, was the remedy only applicable to specific kidney lesion, or was it a remedy for the condition which we know as Bright's disease, but which I prefer to call arterio-sclerosis renal, as this term conveys some idea of the pathology of the condition.
WHITEHEAD WH. THE PATHOLOGIC ANALOGY OF BRIGHT'S DISEASE AND SYPHILIS. JAMA. 1898;XXXI(6):277–279. doi:10.1001/jama.1898.92450060015001d
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