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Substitution as generally understood is one of the abominable evils against which physicians have to be on their guard. The only way to get rid of this evil is for a physician to insist on having his prescriptions filled by a reliable druggist, and then watch this druggist occasionally to see that he does not fall from grace. The reputation of the physician, the health, and sometimes life, of the patient depend on the correct filling of prescriptions. Whilewe believe that very few druggists are guilty of substitution, some of them are. We refer now to the substitution of "something just as good" for a similar preparation and which the druggist may believe will answer the purpose, especially if it is cheaper. But the druggist who places his "belief" above the written instructions of the physician will be dishonest in other ways and should be treated accordingly. Our attention, however,
SUBSTITUTION EXTRAORDINARY.. JAMA. 1902;XXXVIII(1):39. doi:10.1001/jama.1902.02480010043011
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