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Article
February 8, 1902

PROTECTIVE INOCULATION AGAINST TYPHOID FEVER.

JAMA. 1902;XXXVIII(6):404. doi:10.1001/jama.1902.02480060042009
Abstract

The testimony of British military surgeons in South Africa continues favorable to the usefulness of inoculation with sterile cultures of the typhoid bacillus in reducing the mortality from typhoid fever and in diminishing the severity of the disease. According to the most recent report, as made by Major C. Birt,1 there occurred at Harrismith, between September, 1900, and September, 1901, 1210 cases of typhoid fever, of which 947 were among uninoculated and 263 among inoculated individuals. Of the uninoculated, 135 died, or 14.25 per cent.; of the inoculated, 18 or 6.8 per cent. The average duration of the pyrexia was 28 days in 317 cases in uninoculated persons, and 15 days in 151 cases in inoculated persons, the average maximum temperature in the former being 103.7, in the latter 102.9. The percentage of cases among the uninoculated in which relapse took place was 24, as against 6 among the

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