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February 22, 1902

Inhalation and Atomization.

JAMA. 1902;XXXVIII(8):526. doi:10.1001/jama.1902.02480080036014

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Chicago, Feb. 17, 1902.

To the Editor:  —On page 474 of The Journal of February 15, it is stated that "It is yet a question as to how much of the respiratory tract is reached by inhalations." I am surprised that the writer of the above is ignorant of the experimental work that I have done in this line. It is now positively proven that nebulized medicaments reach the pulmonary alveoli of the human lung, of the lung of dogs and of guinea-pigs. The microscopic slides which are the proof of this contention and statement are in my possession, and unquestionably prove the truth of this assertion. As far back as May 28, 1898, The Journal published an article by me on "Experimental Work on the Penetrability of Vaporized Medicaments into the Air Passages." This proved the existence of nebulized medicaments in the lung of a human being. Since then

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