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March 8, 1902


JAMA. 1902;XXXVIII(10):649-650. doi:10.1001/jama.1902.02480100025004

The healing of nerves is a subject of much scientific as well as actual, practical interest. At the present time most investigators hold that when a peripheral nerve regenerates, either after division or degeneration, the peripheral segment undergoes "neurotization" from the end of the proximal portion. This means that the ends of the axons above the point of division or degeneration grow out into the distal part of the nerve, the continuity of which is thereby restored. Clinical surgery teaches that this process may require weeks and months for its completion. But there is another view, at the present time held by a small number only, which teaches that in nerve regeneration axons, medullary sheaths, and neurilemmata are formed from cells in the distal segment, called neuroblasts, and that the fusion of the different parts thus produced with one another and with the central part restores the continuity of the