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March 8, 1902


JAMA. 1902;XXXVIII(10):650. doi:10.1001/jama.1902.02480100026005

The impression is gaining ground that besides disease-conditions due to absence of the thyroid gland or total inhibition of its secretion, there are also functional deficiencies of thyroid secretion that produce recognizable symptoms. These symptomatic conditions have proved utterly obstinate to treatment, as a rule, up to the present time because of failure to recognize their cause. Two recent contributions to the subject show that the therapy of these conditions is very encouraging when their true etiology is recognized and that the diagnosis is not difficult if suspicions of the nature of the fundamental disturbance of metabolism are aroused. The therapeutic test of the administration of thyroid extract and its good effect makes the diagnostic conclusions absolutely certain.

Dr. Heinrich Stern1 recently called attention to the fact that juvenile obesity is not infrequently accompained by a tendency to tachycardia, with symptomatic dyspnea on exertion. These conditions are more common