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Fuetterer deals interestingly, in an original article in this issue, with one phase of the cancer question, namely, the frequency with which benign ulcers of the stomach are transformed into carcinomata. Moreover, he believes that such change may take place in small and recent ulcers as well as in large chronic ones, and cites instances. Furthermore, he thinks that the degenerative changes first occur in the edges or the ulcer, rather than at its base. There is no doubt, as he says, that the constant irritation to which gastric ulcers are exposed, especially those near the pylorus, strongly predisposes them to undergo malignant degeneration. This is an important statement, and is undoubtedly true; since, according to the best authorities, practically three-fourths of all gastric ulcers are at or near the pylorus, occupying the constricted segment of the stomach rather than its expanded portion, or larger segment. So careful a man
ETIOLOGY OF CARCINOMA. JAMA. 1902;XXXVIII(11):711–712. doi:10.1001/jama.1902.02480110033005
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