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April 12, 1902


Author Affiliations

Tutor in Pathology, College of Physicians and Surgeons, Columbia University. NEW YORK CITY.

JAMA. 1902;XXXVIII(15):930-938. doi:10.1001/jama.1902.62480150024001d

INTRODUCTION.  The conception of the bacillus coli communis* as a pathogenic factor in disease begins with its earliest history; and the suspicion at first entertained of a possible relationship to certain human infections has been confirmed from many sources. But with the early development of the idea of pathogenic significance the organism was given undue prominence in disease. Whilst its association with a multitude of lesions as different in distribution as they are varied in character is now clearly established, the closer studies of the last few years indicate that its inciting part is certainly one of less independence than many writers are disposed to admit.Recent investigations which have enlisted more exact and more comprehensive methods of technique reveal in the lesions in which the colon bacillus is so commonly found, other micro-organisms, especially pyogenic cocci, and sometimes bacteria of the anaërobic class1 whose primary importance is more

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