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Carcinoma of the axilla consecutive to a primary focus of the disease in the mammary gland, or some other organ or structure, is a matter of almost daily occurrence in the experience of the surgeon. But primary carcinoma of the axillary region is rare enough to be worthy of discussion, especially as it raises some important questions in the fields of histologic anatomy and pathology, and of practice. There is no apparent reason why this region might not be the site of the squamous celled, or true skin carcinoma, as frequently as any other in the body. Primary cancer of the axillary skin is, however, exceedingly rare. Of 7297 primary cases of carcinoma analyzed by Williams 571 were of the skin, but of these latter only three were axillary.
There is no doubt but that occasionally a primary carcinoma of the breast will first manifest itself clinically through the infection
GRAHAM DW. PRIMARY CARCINOMA OF THE AXILLA. JAMA. 1898;XXXI(9):445–447. doi:10.1001/jama.1898.92450090011001c
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