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Medical literature can give us no definite data as to when this peculiar affection was first regarded as a distinct and separate disease. Unmistakable cases were reported in the sixteenth century, and since that time the disease has been becoming steadily more and more prevalent. The fact that there is a hay fever association in this country, which has records of over two hundred thousand cases, will show how extremely common the affection is in the United States. Indeed, this country and England are its principal seats, the inhabitants of Germany, France and other countries of continental Europe affording comparatively few cases. It might be stated here as a rather curious fact that hay fever is but infrequently encountered among immigrant Germans (Jacobi) and French, even in the regions where native English and Americans are particularly prone to attacks.
Since its earliest discovery the cause or causes of hay fever
HAY FEVER. JAMA. 1898;XXXI(9):474–475. doi:10.1001/jama.1898.02450090040005
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