The following analysis of a large number of instances of tetanus in the course of or following vaccinia, was prompted by the occurrence of a case in the practice of the writer, and by its fatal termination in spite of an early diagnosis and heroic treatment. During the five months that have succeeded the report of this case before the Philadelphia County Medical Society an attempt has been made to ascertain the details of such a number of similar cases, both in recent and past years, as would warrant a conclusion as to the source of the tetanus infection.
The proportions of this task can be realized only in part even by those who have engaged in similar work. There is abundant indication that tetanus has occasionally appeared in the course of and following vaccinia from the time of Jenner down to the present day, and it will be noted
WILLSON RN. AN ANALYSIS OF FIFTY-TWO CASES OF TETANUS FOLLOWING VACCINIA.WITH REFERENCE TO THE SOURCE OF INFECTION. 1839-1902.. JAMA. 1902;XXXVIII(18):1147–1152. doi:10.1001/jama.1902.62480180025001f
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