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May 10, 1902

AN ANALYSIS OF FIFTY-TWO CASES OF TETANUS FOLLOWING VACCINIA.WITH REFERENCE TO THE SOURCE OF INFECTION. 1839-1902.

JAMA. 1902;XXXVIII(19):1222-1231. doi:10.1001/jama.1902.62480190028001g
Abstract

In order to study the question in a judicial manner, and to weigh the evidence for and against an infection carried by the vaccine virus, several points must at once be considered, and in their association and grouping rather than separately. Among these are to be included:

  1. The manner of preparation of the virus, the suddenness and proportions of the demand for the same, the care used in testing such virus before being placed upon the market, and finally, the bacteriologic and inoculation experiments that have been possible either before or after infection.

  2. The method of vaccination; whether executed in an aseptic fashion, andwith such precautions as to prevent unnecessary exposure of the wound during and after the operation.

  3. The after-care of the wound, up to and after the time of perfect healing and the dressing employed.

  4. The incubation period of the tetanus, always allowing (with a view to thoroughness

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