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Article
May 31, 1902

NEED OF MUCH MORE ACCURATE KNOWLEDGE CONCERNING BOTH THE IMMEDIATE AND REMOTE EFFECTS OF THE REMEDIAL AGENTS IN GENERAL USEAND THE EXERCISE OF MORE CARE TO AVOID THE COINCIDENT ADMINISTRATION OF ANTAGONISTIC REMEDIES IN ACUTE DISEASES.

JAMA. 1902;XXXVIII(22):1415-1418. doi:10.1001/jama.1902.62480220001001
Abstract

Perhaps the three most important defects in practical medicine of the present day, as seen both at the bedside and in works on therapeutics and practice of medicine, are: First, failure to fully appreciate the fact that all diseases are deviations from the natural standard of action or of structure in some part or in the whole of the living body, caused by either mental or physical influences, and progressing towards recovery or death in accordance with known laws of vital resistance; second, inadequate knowledge of the physiologic laws and processes that constitute the vital resistance of living bodies to the action of the various causes of disease; third, the imperfect knowledge of the action of many of the most important remedies in the materia medica, and consequently their frequent erroneous or even antagonistic use.

THE NEED OF KNOWLEDGE OF VITAL PROCESSES.  A knowledge of the causes of diseases both

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