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Article
June 14, 1902

THE CURATIVE ACTION OF FLUORESCENCE IN MALARIA.

JAMA. 1902;XXXVIII(24):1581-1582. doi:10.1001/jama.1902.02480240031011
Abstract

The various forms of phototherapy and radiotheraphy have excited much attention recently and are being given extensive trial in various diseases, especially of the skin. Dr. A. F. A. King in recent articles2 brings forward a number of facts to show that the curative action of quinin in malaria may be due to its fluorescence whereby it produces violet rays of light in the blood. King starts from the assumption that the malarial ameba like Ameba proteus streams in red light, but not in violet, hence quinin would arrest sporulation of the malarial parasite. As further evidence, King cites the fact that two other vegetable products, namely esculin and fraxin, both of which produce a blue florescence, are effective remedies for malaria. King then goes on and shows that in 1886 Henry Bence Jones discovered a fluorescent substance in the tissues of guinea-pigs and of man, which substance he

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