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Article
June 28, 1902

VARIETIES OF ENDOCARDITIS.

JAMA. 1902;XXXVIII(26):1692. doi:10.1001/jama.1902.02480260012005
Abstract

Endocarditis, like the inflammatory process in general, may result from a variety of irritating factors, mostly bacterial in character. In consequence of the reaction between the morbific agents and the invaded tissues, there may develop irregular roughening or elevation of the endocardial surface, or polypoid or villous formations, or ulcerations, or even suppuration, representing the different pathologic types of endocarditis, with corresponding clinical variations. The several lesions would seem to be the expression of modifications in the intensity of the morbid process rather than of any specific pathogenic activity on the part of the causative micro-organisms. Some observations in support of this view were communicated at a recent meeting of the Royal Medical and Chirurgical Society by Drs. F. J. Poynton and Alexander Paine,1 who had previously isolated from the blood, during life, in cases of acute rheumatism and from the lesions after death a diplococcus susceptible of

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