Cases of congenital ectopia lentis may, for convenience of reference, be divided into three groups: first, those occurring in one member of the family; second, those occurring in several members of the same family; and third, those occurring in one or more members of a family for two or more generations.
The malformation is not commonly met with, as out of fifty thousand hospital and private patients of Knapp's in New York City, only ten (1 in 5000) were seen. Notwithstanding this, however, illustrations of individual cases (group I) are quite numerous in literature, and probably number about a hundred.
Examples of the malposition occurring in more than one member of the same generation of a family (group II) are also on record to the number of twenty. Instances of the ectopia in several members of the same family for several successive generations (group III) are quite rare and far
PARKER EF. FIVE CASES OF CONGENITAL, BILATERAL, SYMMETRICAL DISPLACEMENT OF THE LENS OF THE EYE IN THREE SUCCESSIVE GENERATIONS OF ONE FAMILY. JAMA. 1898;XXXI(13):708–710. doi:10.1001/jama.1898.92450130027002j
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