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Few opinions are more firmly held or more dogmatically taught than that opium must not be given to patients with albuminuria or Bright's disease. The more extreme upholders of this doctrine teach that the presence of albumin in the urine, even when the kidneys are not diseased, as in cases of fever, prohibits the use of opium. Many years of careful investigation of this subject convince me that this opinion is wrong. I avail myself of this opportunity to again draw attention to this subject. Several writers in America and England have recorded their experiences that opium either by the mouth or hypodermically may be administered, not only without danger but with great advantage, to some patients with uremia. Dr. Loomis ("Diseases of Respiratory Organs, Heart and Kidneys," 1875) states that he has employed morphia hypodermically in puerperal eclampsia with marked success. He says that morphia may be given hypodermically
RINGER S. THE USE OF MORPHIA IN BRIGHTS DISEASE. JAMA. 1898;XXXI(15):817–818. doi:10.1001/jama.1898.92450150003001a
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