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October 29, 1898

CREOSOTE NOT A SPECIFIC.

JAMA. 1898;XXXI(18):1062. doi:10.1001/jama.1898.02450180056008

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Abstract

The drug, creosote, has become so inseparably connected in history, in clinical experience, and in present day teachings, with the disease of pulmonary tuberculosis, that its acceptance as a specific becomes a natural consequence. Such empiricism, however, is fatal to the scientific treatment of tuberculosis even though creosote does seem to be indicated in every case. Creosote probably exercises its curative action in the lung because of its physiologic property of stimulating the bronchial mucosa, where it is eliminated, and its action as an expectorant; not as a specific for the disease of tuberculosis.

The healthy human body is not susceptible to infection by the germs of tuberculosis because a vital resistance of the tissues prevents the development of any bacteria that may gain entrance, and those bacteria that develop in a lung to cause a miliary tuberculosis, do so because—from malnutrition, lack of exercise, the inhalation of sewer gas

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