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This question was asked in an editorial of the Journal of the American Medical Association of July 23, 1898, the writer in his comments seeming to intimate that the subject has been complicated rather than simplified by some of the more modern observations, and that it is surrounded by needless mystery.
It is true that the diagnosis is not quite so simple as in the days when "albuminuria" covered almost the whole ground of renal pathology, while prognosis was brief and gloomy, and the clinical history prolix only, because of the great variety and severity of the symptoms which might precede the fatal termination. That, however, was longer ago than the "few years" claimed by the editor. Forty years ago it was known that albumin was to be found in the urine in many cases which were not to be considered Bright's disease, and the number of conditions in which
EDES RT. WHAT ARE THE SYMPTOMS OF NEPHRITIS?. JAMA. 1898;XXXI(19):1093–1099. doi:10.1001/jama.1898.92450190017002f
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