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Article
November 12, 1898

SOME EXPERIMENTS IN URIC ACID—UREA.EXCRETION BY THE KIDNEYS IN AN INDIVIDUAL UPON A MILK DIET, AND IN A CASE OF RECURRENT MELANCHOLY.

JAMA. 1898;XXXI(20):1150-1153. doi:10.1001/jama.1898.92450200018001h
Abstract

I. MILK DIET.  Before the Section on General Medicine at the semicentennial meeting of the Association the writer presented a study of "The Rôle of Uric Acid in Neurasthenia and Allied States," 1 and drew the conclusions from the investigation that uric acid and its congeners must be potent causes in many cases of neurasthenia and other like nervous disorders, or must again cause aggravation of essential cases. Since that time further experiments as to the knowledge needed of internal metabolism and the significance of the amount of uric acid excretion to such bodily disturbance have been carried out; and, as first suggested in the paper quoted, the quantitative determination of uric acid on a milk diet has been sought for.Dr. S.Weir Mitchell kindly selected a private case of exaggerated subconscious-self (hysteria) and of mild functional nerve tire at the Infirmary of Nervous Diseases for my urinalyses. This woman

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