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November 12, 1898


JAMA. 1898;XXXI(20):1156-1160. doi:10.1001/jama.1898.92450200024001j

In a paper read before the Philadelphia Neurological Society in 1891, Henry1 reported the case of a married woman, 63 years old, in whom, at the age of 49, somewhat circumscribed, painful, fatty swellings appeared successively in various parts of the body. The patient was an immoderate drinker and had had epileptiform convulsions frequently in infancy. Menstruation had begun at 11 and had ceased abruptly at 35. Sensibility was impaired in proportion to the deposition of fat. The case was described as one of myxedematoid dystrophy, and for the condition the designation paratrophy was proposed. In a paper read before the American Neurological Association in 1888, Dercum2 reported the case of a widow, 51 years old, in whom the arms began to enlarge at the age of 48 or 49 and were the seat of pain. Back, shoulders, arms and sides of the chest became the seat of