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The object of the present paper is to point out those peculiarities of headaches which, can serve as guides in the search for their origin. The author's experience pertains principally to headaches dependent upon affections of the special senses. But valuable lessons, too, have been learned—in a negative sense—from the study of those cases which, on investigation, proved to be of different character.
Before proceeding to details, I wish to explain the point of view from which I have been led to regard headaches of peripheral origin. While I agree with the general experience, that a large number of headaches start from some anomaly of the eyes or of the nose, I do not think that the detection of such a peripheral origin ends the investigation of the case. We must consider not merely the peripheral lesion, but also the condition of the nervous system. There are, indeed, certain peripheral
GRADLE H. DIAGNOSTIC CHARACTERISTICS OF HEADACHES ACCORDING TO THEIR ORIGIN. JAMA. 1898;XXXI(21):1222–1225. doi:10.1001/jama.1898.92450210023002g
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