It has recently been established that the typhoid bacillus may occur in enormous numbers in the urine, in the course of typhoid fever. Richardson1 of Boston, showed that in 38 cases of typhoid fever, the bacilli were present in the urine of 9, always in large numbers and in practically pure cultures; the bacilli appeared first in the later stages of the disease, and persisted in most of the cases far into convalescence. The bacilli were nearly always associated with albuminuria and casts. Horton Smith2 examined the urine in 7 typhoid patients, with 3 positive results; he observed that the organisms may be so numerous that the urine becomes distinctly turbid on that account. Petruschky3 examined the urine in 50 cases of typhoid fever, with 3 positive results. The first case retained the bacilli in the urine for two months after the temperature had become normal: the second
THE PRESENCE OF THE BACILLUS TYPHOSUS IN THE URINE IN TYPHOID FEVER. JAMA. 1899;XXXII(11):617–618. doi:10.1001/jama.1899.02450380047006
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