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According to the Swiss correspondent of the Lancet, Fräulein Hoffenhausen details in a graduation thesis the results of a histologic study of the vermiform appendix in thirty fatal cases of typhoid fever. In most instances the appendix exhibited changes similar to those present in the large intestine—principally inflammation of the mucosa, with cellular infiltration. Less commonly specific lesions were found, but not of sufficient intensity to occasion pronounced or characteristic symptoms.
STATE OF THE VERMIFORM APPENDIX IN TYPHOID FEVER. JAMA. 1899;XXXII(19):1065. doi:10.1001/jama.1899.02450460049014
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