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June 10, 1899


Author Affiliations

Clinic Professor of Laryngology and Rhinology in the Jefferson Medical College; Consulting Laryngologist, Rhinologist and Otologist to St. Agnes' Hospital, Etc. PHILADELPHIA.

JAMA. 1899;XXXII(23):1298-1299. doi:10.1001/jama.1899.92450500024003c

Within the past few years there has been considerable investigation as to the import of bacteria present within the nasal chambers, and the relation of such bacteria as causal factors in disease processes. Opinions differ as to the presence of pathogenic bacteria in the normal nasal secretions and normal membranes. This raises the question as to what constitutes a normal nasal mucous membrane. While the membrane may be normal as to its function, yet the construction of the nasal cavity may be such as to permit of the accumulation of normal secretion within that cavity. This accumulated normal secretion forms a suitable nidus for the lodgment of dust and other irritating materials, which would soon cause local alteration, besides perverting secretion and being nutrient media for the development of bacteria, which are constantly being inhaled and find lodgment in the localized irritated areas. Inoculations from a nasal cavity, in which,