If therapeutics can be defined, "the knowledge of indications and the art of fulfilling them," it can be safely asserted and successfully maintained that the possession of so-called specific medications has been the signal of a retrograde step. No one will deny, for instance, the meager reflection accorded by the majority of medical men to the proper use and administration of such specific medicaments as mercury and quinin. The choice of the remedy being determined in advance, it would seem that nothing important remained to be considered; common sense is excluded by empiricism, and force of habit crowds out the allimportant question of indications. In no other morbid entity is such culpable disregard manifested as in syphilis. When questioned regarding the mode of treating this disease, the majority of practitioners invariably outline in two words, a simple, constant and uniform method; no reasons are given; no questions asked. The diagnosis
TAIT D. TREATMENT OF SYPHILIS. BY BACCELLI INTRAVENOUS INJECTIONS OF MERCURY. JAMA. 1899;XXXII(24):1361–1363. doi:10.1001/jama.1899.92450510010003b
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