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June 24, 1899

An Experimental Research Into Surgical Shock. An Essay awarded the Cartwright Prize for 1897.

JAMA. 1899;XXXII(25):1461-1462. doi:10.1001/jama.1899.02450520059031

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This volume gives the details and results of an experimental study of surgical shock, begun at University College, London, and completed in the Cleveland College of Physicians and Surgeons. After a brief historic review and a description of apparatus, the details of 138 experiments on dogs are given, the respiration and circulation being registered on self-recording instruments. Each region and tissue of the body was studied as regards its relation to shock, and the results are discussed at length. The general conclusion from all the data is that surgical shock is mainly due to impairment or breakdown of the vasomotor mechanism, and that all the factors causing collapse may add to shock. The cardiac and respiratory factors may have a certain importance, but the main action is on the vasomotor system. The author makes a distinction between collapse and shock, understanding by the former term the immediate depression or death

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