Most of the effort heretofore to arrive at an estimation of hemoglobin in blood has been made by means of the various color tests. These tests have multiplied until the catalogue of the various instruments resembles the list of "sure cure" remedies for the hives. This fact alone shows a dissatisfaction on the part of the clinician with the results obtained by the various color methods. The two instruments with which we are most familiar in this country are Von Fleischel's hemometer (the German), and Gower's (the English instrument.) The use of these instruments has demonstrated the sources of error as enumerated.
In color tests in general:
Two eyes rarely agree in accurate estimation of varying shades of color, thus producing individual variations.
Eyes of the same individual vary at different times, due to fatigue and influence of varying ntensity of light.
I have made a test of 425 cases
LINNELL BM. ESTIMATION OF HEMOGLOBIN. A COMPARISON OF THE VARIOUS METHODS. JAMA. 1899;XXXIII(1):19–22. doi:10.1001/jama.1899.92450530019002c
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