Man is a compound organism made up of many different organs, structures and systems which have their own life, albeit subordinate to the life of the organism as a whole. These structures, organs, etc., draw on a fixed supply of the nutriment and unless this nutriment be properly distributed through the system of checks summed up in the nervous system one organ or structure will receive more than its due proportion of nutriment. The balance kept up by the checks is distributed when the organism becomes nervously exhausted either from nerve-tire, from general disease, or from other cause. If this exhaustion occurs at certain periods, called the periods of stress, or of involution and evolution, certain structures on which is thrown such stress are peculiarly apt to be affected either in the direction of arrested development or of hypertrophy. Prominent among the structures which mark these periods are the jaws
KIERNAN JG. HUMAN FACE AND JAWS. AS A DANGER SIGNAL OF SYSTEMIC DEFECT OR DISORDER. JAMA. 1899;XXXIII(2):81–82. doi:10.1001/jama.1899.92450540023002h
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