The flesh food which is taken into the human system consists of proteids with about .3 per cent. of creatin. The nitrogenous waste which is thrown out of the system by the kidneys consists of urea with about .3 per cent. of creatinin, the latter being an anhydrid of creatin. We would therefore be inclined to the belief that the proteids, when they have served their purpose in the human economy are eliminated as urea and the creatin as creatinin. The proteids are essential in a dietary because they repair muscular waste, and this waste is excreted as urea; but the excreted urea is not a measure of the muscular waste for when an excess of proteids is ingested that which is not required for metabolic processes is oxidized to urea with the production of heat and energy, and immediately eliminated. The ingestion of an excess is followed so promptly
VALUE OF MEAT EXTRACTS.. JAMA. 1899;XXXIII(3):166. doi:10.1001/jama.1899.02450550050007
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