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Article
July 22, 1899

CEREBROSPINAL MENINGITIS.

JAMA. 1899;XXXIII(4):188-192. doi:10.1001/jama.1899.92450560008001c
Abstract

Cerebrospinal meningitis is probably a microbic disease. Recent researches prove that the diploccoccus intracellularis meningitidis of Weichselbaum is the active causative agent in producing the disease. Cerebrospinal meningitis has appeared at different times and in widely separated regions in an epidemic form, remaining in the same regions as an endemic disease, and manifesting itself in sporadic cases. There was such an epidemic in Northern Illinois in 1878 and 1879, and to the sporadic cases following that scourge and coming under my own personal care this paper will be devoted.

It is not my purpose to enter exhaustively into the history of cerebrospinal meningitis, which must be familiar to you all. It will suffice for our purpose to say that preceding the beginning of the nineteenth century we have no clearly defined and sharply outlined picture of this disease. Visseux of Geneva gave, in 1805, the first clear clinical record of

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